Rimegepant for Endometriosis

CS
Overseen ByClinical Studies Unit
Age: 18 - 65
Sex: Female
Trial Phase: Phase 2
Sponsor: Mayo Clinic
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to evaluate the efficacy of rimegepant 75 mg versus placebo in reducing endometriosis-associated pain (EAP) in women with moderate-to-severe pain and histologically confirmed endometriosis.

Who Is on the Research Team?

YW

Yohannes Woldeamanuel, MD

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

This trial is for women who have been diagnosed with endometriosis through tissue testing and are experiencing moderate to severe pain from the condition.

Inclusion Criteria

I have moderate to severe pain from endometriosis.
I was diagnosed with endometriosis by surgery within the last 3 to 6 months.
Current use of an effective method of contraception and commitment to continue the same method throughout the 12-week study
See 2 more

Exclusion Criteria

Participation in another investigational drug or device trial within 30 days prior to screening
Inability to comply with study procedures including daily electronic EDPI diary and mandatory in-person clinic visits
Women not currently using an effective method of contraception
See 5 more

What Are the Treatments Tested in This Trial?

Interventions

  • Rimegepant

Trial Overview

The study compares rimegepant (a medication taken at a dose of 75 mg) to a placebo, to see if it helps reduce pain caused by endometriosis. Participants are randomly assigned to either group.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: RimegepantExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+