Ketamine for Depression and Anxiety

ST
Overseen ByStudy Team
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Stanford University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this open-label study is to evaluate the effects of a single intravenous infusion of ketamine on depression and anxiety in adults with low vision.

Who Is on the Research Team?

CI

Carolyn I Rodriguez, MD, PhD

Principal Investigator

Stanford University

Are You a Good Fit for This Trial?

This trial is for adults with low vision who are experiencing depression or anxiety. Participants must be able to safely receive ketamine and not have any medical conditions that would make the treatment unsafe.

Inclusion Criteria

Healthy Controls: Likely able to tolerate clinical study procedures
Healthy Controls: No current or lifetime psychiatric diagnosis
Participants with Low Vision: Qualifies as a low vision participant based on ophthalmology assessments
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Exclusion Criteria

Participants with Low Vision and Healthy Controls: Allergy to ketamine
Participants with Low Vision and Healthy Controls: Pregnant or nursing, or able to become pregnant and are not practicing an effective means of birth control
Participants with Low Vision and Healthy Controls: Any current or past medical/psychiatric condition that makes participation unsafe in the opinion of the investigator or study physician

What Are the Treatments Tested in This Trial?

Interventions

  • Ketamine

Trial Overview

The study is testing a single intravenous dose of ketamine to see how it affects symptoms of depression and anxiety in adults with low vision. All participants will know they are receiving ketamine (open-label design).

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Low VisionExperimental Treatment1 Intervention
Group II: Healthy ControlsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Stanford University

Lead Sponsor

Trials
2,527
Recruited
17,430,000+