Povidone-Iodine for Dental Implants

ZC
KS
Overseen ByKevin Smith, DMD, FACS
Age: 18 - 65
Sex: Any
Trial Phase: Phase 1 & 2
Sponsor: Madigan Army Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

We hope to learn if applying antiseptic to the inside of a dental implant will decrease or alter the types of bacteria inside it which may then decrease the incidence of implant failure associated with bone loss, infection, and other complications. During your implant placement appointment, an antiseptic (povidone iodine) will be applied to the inside one of your two new dental implants, no antiseptic will be applied to your other dental implant (this is what would occur if you choose not to participate in this study), before covering both of them with a cover screw or healing abutment. You will return to the Madigan Oral \& Maxillofacial Surgery Clinic 3-6 months later when your implant hardware is removed a swab of the implants internal cavities will be collected. Your participation in this research will last up to 6 months and require one additional minute during both your implant placement and hardware removal appointments.

Who Is on the Research Team?

KS

Kevin Smith, DMD, FACS

Principal Investigator

Madigan Army Medical Center

Are You a Good Fit for This Trial?

This trial is for people who are getting two new dental implants and are willing to have an antiseptic applied to one of them during placement. There are no specific inclusion or exclusion criteria listed.

Inclusion Criteria

Active Duty Military
Over 6 months remaining at local duty station (Joint Base Lewis McChord)
I am between 18 and 55 years old.
See 1 more

Exclusion Criteria

I am taking medications that affect how my bones or soft tissues heal.
Tobacco user
Pregnant at time of enrollment (these surgeries are not typically performed on pregnant women)
See 3 more

What Are the Treatments Tested in This Trial?

Interventions

  • Povidone-Iodine

Trial Overview

The study tests whether applying povidone-iodine (an antiseptic) inside one dental implant, compared to not using any antiseptic in the other, affects bacteria levels and may help prevent complications. Each person serves as their own control.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Case-Control GroupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Madigan Army Medical Center

Lead Sponsor

Trials
52
Recruited
17,600+