Empagliflozin for Breast Cancer

(EMBRACE Trial)

PG
Overseen ByPamela Grizzard
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Virginia Commonwealth University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The primary objective of this pilot study is to evaluate the feasibility and acceptability of a clinical trial protocol investigating 10 mg/day empagliflozin in breast cancer patients receiving anthracycline-based chemotherapy.

Who Is on the Research Team?

EP

Elisa Palladino, Ph.D

Principal Investigator

Virginia Commonwealth University

Are You a Good Fit for This Trial?

This trial is for people with breast cancer who are about to start anthracycline-based chemotherapy. Participants should be able to safely take empagliflozin and follow the study procedures.

Inclusion Criteria

I am scheduled to get anthracycline chemotherapy, possibly with hormone therapy.
I can walk two blocks without chest pain, shortness of breath, or fainting.
I am between 18 and 85 years old.
See 4 more

Exclusion Criteria

I have frequent abnormal heartbeats, more than 20 per minute.
Recent history of alcohol or drug abuse
Claustrophobia
See 11 more

What Are the Treatments Tested in This Trial?

Interventions

  • Empagliflozin

Trial Overview

The study is testing if taking 10 mg of empagliflozin daily is practical and acceptable for breast cancer patients during their chemotherapy. It focuses on how well patients can stick to this added medication.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: EmpagliflozinExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Virginia Commonwealth University

Lead Sponsor

Trials
732
Recruited
22,900,000+