Hyperbaric Oxygen Therapy for Traumatic Brain Injury
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this study is to examine changes in blood biomarkers following hyperbaric oxygen therapy (HBOT) in military veterans with traumatic brain injury and persistent post-concussive symptoms. The main questions it aims to answer are:
1. Does HBOT produce measurable changes in inflammatory, neurotrophic, and neuronal injury biomarkers from baseline to completion of a 40-session treatment protocol in veterans with TBI and PCS?
2. Does the presence of comorbid PTSD influence biomarker responses to HBOT among veterans with TBI and PCS?
Participants will:
Complete medical and behavioral health evaluations to determine eligibility. Provide blood samples before treatment and after the final session. Receive 40 HBOT sessions at 2.0 ATA, generally two sessions per day with at least four hours between sessions.
Approximately 34 veterans will participate. All participants will receive HBOT; there is no comparison group.
Who Is on the Research Team?
Steve Wyman, MD
Principal Investigator
Summit Hyperbarics and Wellness
Are You a Good Fit for This Trial?
This trial is for military veterans who have had a traumatic brain injury and still have ongoing symptoms after a concussion. Veterans with or without PTSD can join, but they must pass medical and mental health checks to make sure it's safe for them.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Hyperbaric Oxygen Therapy (HBOT)
Trial Overview
The study tests hyperbaric oxygen therapy (HBOT), where participants breathe pure oxygen in a pressurized chamber over 40 sessions. Researchers will look at changes in blood markers before and after treatment. All participants receive HBOT; there is no placebo group.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants in this arm will receive 40 hyperbaric oxygen therapy (HBOT) sessions in a multiplace chamber at 2.0 atmospheres absolute (ATA). Each session will include two 30-minute periods of breathing 100% oxygen, separated by a 5-minute air break. Sessions will occur twice daily, Monday through Friday, with at least four hours between sessions.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Summit Hyperbarics and Wellness
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.