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60 Participants NeededMy employer runs this trial

RTx-015 for Retinitis Pigmentosa

(PERCEPT Trial)

Recruiting at 13 trial locations
EM
Overseen ByExecutive Medical Director
Age: 18+
Sex: Any
Trial Phase: Phase 2 & 3
Sponsor: Ray Therapeutics, Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this clinical trial is to evaluate the effectiveness and safety of a single injection into the eye of an investigational gene therapy in participants with retinitis pigmentosa (RP).

Are You a Good Fit for This Trial?

This trial is for people diagnosed with retinitis pigmentosa, an inherited eye disease that causes vision loss. Participants must meet specific medical criteria set by the study and cannot join if they have certain other health conditions or factors that would interfere with participation.

Inclusion Criteria

Able and willing to provide written informed consent prior to any study-specific procedures, in accordance with ICH GCP and applicable regulations
I am 18 years old or older.
Baseline best corrected distance visual acuity (BCVA) in the study eye of LogMAR 1.0 and 2.7 inclusive (approximately 20/200 - 20/9000), measured monocularly at the ETF by certified, masked personnel using grating visual acuity with conversion to logMAR equivalents
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Exclusion Criteria

I am able to attend all study visits and complete required assessments.
I have not joined another clinical trial with a study drug or device in the past 6 months.
Weighing less than 40 kg (88 pounds)
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What Are the Treatments Tested in This Trial?

Interventions

  • RTx-015

Trial Overview

The study is testing a single injection of RTx-015 gene therapy into the eye compared to a sham (placebo) procedure. The goal is to see if RTx-015 can help improve or slow down vision loss in people with retinitis pigmentosa.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Placebo Group

Group I: RTx-015 Lower DoseExperimental Treatment1 Intervention
Group II: RTx-015 Higher DoseExperimental Treatment1 Intervention
Group III: Sham ControlPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ray Therapeutics, Inc.

Lead Sponsor

Trials
2
Recruited
140+

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