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24 Participants NeededMy employer runs this trial

C-1101 for Sciatica

Recruiting at 5 trial locations
SD
AC
Overseen ByAUS Clinical Development Operations
Age: 18+
Sex: Any
Trial Phase: Phase 1
Sponsor: Consano Bio
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to evaluate the safety and tolerability of C-1101 administered as a single dose, transforaminal epidural injection compared to sterile saline

Who Is on the Research Team?

CC

Consano Chief Medical Officer

Principal Investigator

Consano Bio

Are You a Good Fit for This Trial?

This trial is for adults with chronic sciatica (pain from the lower back radiating to or below the knee) who haven't improved with standard treatments and have a BMI under 35.

Inclusion Criteria

My BMI is less than 35.
I have sciatica pain going to or below my knee that hasn't improved with basic treatments.

What Are the Treatments Tested in This Trial?

Interventions

  • C-1101

Trial Overview

The study compares a single injection of C-1101 to a placebo (sterile saline) given into the spine, aiming to see if C-1101 is safe and well-tolerated in people with chronic sciatica.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Group I: Cohort 3 - High doseExperimental Treatment2 Interventions
Group II: Cohort 2 - Mid doseExperimental Treatment2 Interventions
Group III: Cohort 1 - Low doseExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Consano Bio

Lead Sponsor

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