Maridebart Cafraglutide for Obesity
What You Need to Know Before You Apply
What is the purpose of this trial?
The primary purpose of the study is to assess the pharmacokinetics of maridebart cafraglutode after switching from weekly GLP-1RA in participants living with overweight or obesity.
Who Is on the Research Team?
MD
Principal Investigator
Amgen
Are You a Good Fit for This Trial?
This trial is for people who are overweight or have obesity and are currently taking weekly GLP-1 receptor agonist medications. Participants must be able to safely switch from their current medication to maridebart cafraglutide.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Maridebart cafraglutide
Trial Overview
The study is testing how much of the new drug, maridebart cafraglutide, gets into the body after switching from other weekly GLP-1RA medicines in people with overweight or obesity.
How Is the Trial Designed?
6
Treatment groups
Experimental Treatment
Participants will receive maridebart cafraglutide dosing schedule 2 during treatment period
Participants will receive maridebart cafraglutide dosing schedule 1 during treatment period
Participants will receive maridebart cafraglutide dosing schedule 2 during treatment period.
Participants will receive maridebart cafraglutide dosing schedule 1 during treatment period
Participants will receive maridebart cafraglutide dosing schedule 2 during treatment period.
Participants will receive maridebart cafraglutide dosing schedule 1 during treatment period
Find a Clinic Near You
Who Is Running the Clinical Trial?
Amgen
Lead Sponsor
Robert A. Bradway
Amgen
Chief Executive Officer since 2012
MBA from Harvard Business School
Paul Burton
Amgen
Chief Medical Officer since 2023
MD from University of London, PhD in Molecular and Cellular Biology from Imperial College London
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