HM17321 for Obesity
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial focuses on testing a new treatment called HM17321 to assess its safety and effects in the body. It targets healthy adults with a stable weight and a Body Mass Index (BMI) between 20 and 27. The study includes two groups: one receiving HM17321 and another receiving a placebo (a harmless pill with no effect) for comparison. Participants must not have undergone major weight-loss surgeries and should not have certain health issues like uncontrolled thyroid disease or liver problems. The trial aims to gather basic information to aid in developing future obesity treatments. As a Phase 1 trial, participants will be among the first to receive this new treatment, helping researchers understand its effects in people.
Do I have to stop taking my current medications for the trial?
The trial information does not specify if you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is there any evidence suggesting that HM17321 is likely to be safe for humans?
Research shows that HM17321 is being tested for safety in healthy adults. Earlier studies found that most participants tolerated it well, with no serious side effects. Some studies also noted a reduction in body weight and fat, which is promising for obesity treatment. However, as these are early trials, further testing is necessary to fully understand its safety and effects.12345
Why do researchers think this study treatment might be promising?
Unlike the standard obesity treatments, which typically involve lifestyle changes, medications like orlistat, or GLP-1 receptor agonists such as semaglutide, HM17321 is unique because it targets obesity differently. Researchers are excited about HM17321 because it introduces a novel mechanism of action that may offer an alternative route to weight management. While traditional medications often focus on appetite suppression or nutrient absorption, HM17321 could potentially work by influencing metabolic processes directly, offering hope for more effective and faster results.
What evidence suggests that HM17321 might be an effective treatment for obesity?
Studies have shown that HM17321, which participants in this trial may receive, is a promising treatment for obesity. It can help reduce body fat while preserving muscle, offering a significant advantage over current treatments. In animal studies, HM17321 led to weight loss by specifically targeting fat without affecting muscle. This unique method could make it effective for healthier weight loss. Early research suggests that HM17321 could represent a breakthrough in obesity treatment.16789
Are You a Good Fit for This Trial?
This trial is for healthy adults who are interested in participating in a study to test a new potential treatment for obesity. Specific eligibility criteria details are not provided, but typically include certain age and health requirements.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single subcutaneous dose of HM17321 or placebo during a 5-day inpatient stay
Follow-up
Participants are monitored for safety, tolerability, pharmacokinetics, and pharmacodynamics through Day 29
What Are the Treatments Tested in This Trial?
Interventions
- HM17321
Find a Clinic Near You
Who Is Running the Clinical Trial?
Hanmi Pharmaceutical Company Limited
Lead Sponsor
Young Choi
Hanmi Pharmaceutical Company Limited
Chief Medical Officer since 2023
PhD in Pharmacology from Yonsei University
Jae-Hyun Park
Hanmi Pharmaceutical Company Limited
Chief Executive Officer since 2024
MD from Seoul National University