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CBD + THC for Cannabis Impairment

CA
Overseen ByCarlos A Zamarripa, PhD
Age: 18+
Sex: Any
Trial Phase: Phase 1
Sponsor: Johns Hopkins University

What You Need to Know Before You Apply

What is the purpose of this trial?

This study will evaluate the subjective and behavioral effects of cannabis products containing delta-9-tetrahydrocannabinol and cannabidiol

Who Is on the Research Team?

CA

Carlos A Zamarripa, PhD

Principal Investigator

Johns Hopkins University

Are You a Good Fit for This Trial?

This trial is for healthy adults who do not have any major medical or psychiatric conditions and are not currently using cannabis heavily. Participants should not be pregnant, breastfeeding, or taking medications that could interact with cannabis.

Inclusion Criteria

Report using cannabis in the last 3 years, but not in the past month
Negative urine test for illicit drug use (including THC) and negative breath alcohol test (0% breath alcohol concentration) at screening and before study sessions
Have not donated blood in past 30 days
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Exclusion Criteria

I have used psychoactive drugs (not nicotine, alcohol, or caffeine) in the past month.
History of or current evidence of significant medical condition
I have epilepsy or have had seizures in the past.
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What Are the Treatments Tested in This Trial?

Interventions

  • Cannabidiol (CBD)
  • Delta-9-tetrahydrocannabinol (THC)

Trial Overview

The study tests how different combinations of THC and CBD in brownies affect people's feelings and behaviors. Participants will receive brownies with varying amounts of THC (the main psychoactive part of cannabis) and CBD (a non-intoxicating component).

How Is the Trial Designed?

7

Treatment groups

Experimental Treatment

Placebo Group

Group I: 10mg THC + 50mg CBDExperimental Treatment1 Intervention
Group II: 10mg THC + 300mg CBDExperimental Treatment1 Intervention
Group III: 10mg THC + 10mg CBDExperimental Treatment1 Intervention
Group IV: 10mg THC + 100mg CBDExperimental Treatment1 Intervention
Group V: 10mg THC + 0mg CBDExperimental Treatment1 Intervention
Group VI: 0mg THC + 300mg CBDExperimental Treatment1 Intervention
Group VII: 0mg THC + 0mg CBDPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials
2,366
Recruited
15,160,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

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