Axatilimab + CAR-T for Lymphoma
What You Need to Know Before You Apply
What is the purpose of this trial?
Axatilimab + CAR-T in High-Risk Lymphoma
Are You a Good Fit for This Trial?
This trial is for adults (18+) with confirmed large B-cell lymphoma who have high-risk features and are eligible for CAR-T therapy. Participants must have measurable disease, good heart, liver, lung, and kidney function.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive axatilimab in combination with CAR T cell therapy, following a fast-track dose escalation design
Follow-up
Participants are monitored for safety and effectiveness after treatment, with assessments at multiple timepoints
What Are the Treatments Tested in This Trial?
Interventions
- Axatilimab
Trial Overview
The study tests the combination of Axatilimab (an antibody drug) with CAR-T cell therapy in people with high-risk lymphoma to see if this approach works better than standard treatments.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northside Hospital, Inc.
Lead Sponsor
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