This trial is no longer recruiting.My employer runs this trial

MK-7262 + Enlicitide for Healthy Subjects

TF
Overseen ByToll Free Number
Age: 18 - 65
Sex: Any
Trial Phase: Phase 1
Sponsor: Merck Sharp & Dohme LLC
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this study is to learn what happens to a single dose of enlicitide over time in a healthy participant's body when the participant is given a single dose of MK-7262 and what happens to a single dose of MK-7262 over time in a healthy participant's body when the participant is given a single dose of enlicitide.

Who Is on the Research Team?

MD

Medical Director

Principal Investigator

Merck Sharp & Dohme LLC

Are You a Good Fit for This Trial?

This trial is for healthy adults with a BMI between 18 and 32 who have no significant health problems. Participants must be in good overall health before joining.

Inclusion Criteria

I am in good health before starting the study.
My BMI is between 18 and 32.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive a single dose of MK-7262 and enlicitide, with blood samples collected at multiple time points

8 days
Multiple visits for blood sampling

Follow-up

Participants are monitored for safety and effectiveness after treatment, including adverse events

Up to 8 weeks

What Are the Treatments Tested in This Trial?

Trial Overview

The study tests how two drugs, MK-7262 and Enlicitide, interact in the body when given together as single doses to healthy people. Each participant receives both drugs at different times.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Group I: MK-7262 plus EnlicitideExperimental Treatment2 Interventions
Group II: MK-7262Experimental Treatment1 Intervention
Group III: EnlicitideExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Merck Sharp & Dohme LLC

Lead Sponsor

Trials
4,096
Recruited
5,232,000+
Chirfi Guindo profile image

Chirfi Guindo

Merck Sharp & Dohme LLC

Chief Marketing Officer since 2022

Degree in Engineering from Ecole Centrale de Paris, MBA from New York University Stern School of Business

Robert M. Davis profile image

Robert M. Davis

Merck Sharp & Dohme LLC

Chief Executive Officer since 2021

JD from Northwestern University Pritzker School of Law, MBA from Northwestern University Kellogg Graduate School of Management, Bachelor's in Finance from Miami University