80 Participants NeededMy employer runs this trial

Navlimetostat for Drug Interaction Study

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Age: 18 - 65
Sex: Female
Trial Phase: Phase 1
Sponsor: Bristol-Myers Squibb
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to assess the food effect and drug interactions on drug levels of Navlimetostat in health adult female participants

Who Is on the Research Team?

BS

Bristol-Myers Squibb

Principal Investigator

Bristol-Myers Squibb

Are You a Good Fit for This Trial?

This trial is for healthy adult women who cannot become pregnant, have a BMI between 18 and 35, and do not have any significant health issues based on exams and lab tests.

Inclusion Criteria

I am a healthy adult woman who cannot become pregnant and have no major health issues.
My BMI is between 18.0 and 35.0.

What Are the Treatments Tested in This Trial?

Interventions

  • Navlimetostat

Trial Overview

The study is testing how the new drug Navlimetostat interacts with other drugs (Itraconazole, Midazolam, Pantoprazole, Rifampin) and food in healthy women. Participants will receive these drugs to see how they affect Navlimetostat levels.

How Is the Trial Designed?

5

Treatment groups

Experimental Treatment

Group I: Part 4Experimental Treatment2 Interventions
Group II: Part 3Experimental Treatment1 Intervention
Group III: Part 2Experimental Treatment2 Interventions
Group IV: Part 1BExperimental Treatment2 Interventions
Group V: Part 1AExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Bristol-Myers Squibb

Lead Sponsor

Trials
2,731
Recruited
4,127,000+
Headquarters
New York City, USA
Known For
Oncology & Cardiovascular
Top Products
Eliquis, Opdivo, Revlimid, Orencia
Christopher Boerner profile image

Christopher Boerner

Bristol-Myers Squibb

Chief Executive Officer since 2023

PhD in Business Administration from the Haas School of Business, University of California, Berkeley; BA in Economics and History from Washington University in St. Louis

Deepak L. Bhatt profile image

Deepak L. Bhatt

Bristol-Myers Squibb

Chief Medical Officer since 2024

MD from Yale University; MSc in Clinical Epidemiology from the University of Pennsylvania