REGN20423 for Atopic Dermatitis
(AURA-AD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will test a study medicine called REGN20423 to see how effective it is in healthy participants (in Part A) and participants with atopic dermatitis (eczema) (in Part B). REGN20423 is a study medicine that is only used in clinical studies. REGN20423 has not previously been studied in humans.
The study is looking at:
* What side effects REGN20423 might cause
* How much REGN20423 is in the blood at different times
* How well REGN20423 works in adults with atopic dermatitis
* Whether the body makes antibodies against REGN20423
* How the body changes after having REGN20423, which can help researchers understand why REGN20423 works better in some people than others
* What the best dose of REGN20423 is
Who Is on the Research Team?
Clinical Trial Management
Principal Investigator
Regeneron Pharmaceuticals
Are You a Good Fit for This Trial?
This trial is for adults who are either healthy or have had atopic dermatitis (eczema) for at least 6 months. Participants must be in generally good health, with a BMI between 18 and 31, and meet certain eczema severity scores if joining the eczema group.Inclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- REGN20423
Trial Overview
The study is testing REGN20423, a new medicine not previously used in humans, compared to a placebo. It will first test safety and dosing in healthy adults, then see how well it works for adults with atopic dermatitis.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Regeneron Pharmaceuticals
Lead Sponsor
Leonard Schleifer
Regeneron Pharmaceuticals
Chief Executive Officer since 1988
MD and PhD in Medicine
George Yancopoulos
Regeneron Pharmaceuticals
Chief Medical Officer since 1997
MD from Harvard Medical School
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.