KQB368 for Solid Tumors
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this study is to learn if KQB368 works to treat advanced solid malignancies in adults. The study will also learn about the safety of KQB368. The main questions the study aims to answer are:
* What is the safe dose of KQB368 as a monotherapy?
* Does KQB368 decrease the size of the tumor?
* What happens to KQB368 in the body?
Participants will:
* Take KQB368 orally daily in 21-day cycles
* Return to the study site about 7 times in the first 5 weeks, and then once at the beginning of every 21-day cycle after that
Are You a Good Fit for This Trial?
This trial is for adults with advanced solid tumors (like certain lung, uterine, or colorectal cancers) that have a KRAS G12C or G12S mutation. Their cancer cannot be removed by surgery or has spread, and no curative treatments are available. Participants need to have working organs and be able to swallow pills.Inclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- KQB368
Trial Overview
The study tests KQB368 taken daily by mouth in repeating 21-day cycles as the only treatment. It aims to find a safe dose and see if it shrinks tumors in people with specific genetic mutations in their cancer.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Kumquat Biosciences Inc.
Lead Sponsor
Worldwide Clinical Trials
Collaborator
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