Virtual Reality + Psychotherapy for Concussion

(ReVIVE Trial)

This trial aims to determine if combining virtual reality (VR) with regular therapy can enhance thinking skills and reduce stress symptoms in individuals with a history of concussions. Participants will receive either standard care or standard care plus VR, which includes activities like mindfulness and breathing exercises. The trial targets those with mild-to-moderate PTSD symptoms who have served in the military and are currently, or have recently been, in therapy.

As a Phase 1 trial, the research focuses on understanding how the treatment works in people, offering participants the opportunity to be among the first to experience this innovative approach.

Research has shown that virtual reality (VR) aids recovery from brain injuries, with positive results in 10 out of 11 studies. VR might enhance certain mental skills after a brain injury. However, some participants have reported "cybersickness," similar to motion sickness, causing dizziness or nausea.

Regarding safety, these studies indicate that most people tolerate VR well, but monitoring for cybersickness is crucial. Participants can then stop or adjust VR activities if discomfort arises.

Researchers are excited about the use of virtual reality (VR) combined with psychotherapy for treating concussions because it offers a unique approach to rehabilitation. Unlike standard care, which typically involves routine psychotherapy and medication management, this treatment incorporates immersive VR activities that support emotional regulation and cognitive functioning. The VR sessions include interactive activities like mindfulness and grounding techniques, simulating everyday environments to enhance functional rehabilitation. This innovative method not only aims to make therapy more engaging but might also accelerate the recovery process by providing a more comprehensive sensory experience.

Research has shown that virtual reality (VR) can aid in treating traumatic brain injuries (TBI). In 10 out of 11 studies, participants using VR therapy showed improvement, particularly in movement and cognitive skills. These studies often focus on enhancing movement and brain function. In this trial, participants in the "ReVIVE Virtual Reality + Standard Care" arm will receive VR-based rehabilitation alongside standard care. VR adapts exercises based on real-time feedback to meet individual needs, suggesting it might help reduce PTSD symptoms, such as being easily startled, and improve cognitive skills in people with mild traumatic brain injury (mTBI).⁶⁷⁸⁹¹⁰