LY3873862 for ALS
What You Need to Know Before You Apply
What is the purpose of this trial?
The main purpose of this study in participants with Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS) is to test the safety of different doses and to determine the amount of LY3873862 that gets into the bloodstream and how long it takes the body to get rid of it. For each participant, the study will last up to approximately 13 weeks and will include 6 clinic visits.
Who Is on the Research Team?
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Principal Investigator
Eli Lilly and Company
Are You a Good Fit for This Trial?
This trial is for people diagnosed with either sporadic or inherited ALS (Lou Gehrig's disease). Participants must meet certain health requirements, but specific inclusion and exclusion details are not provided here.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- LY3873862
Trial Overview
The study is testing different doses of a new drug called LY3873862 compared to a placebo. Some participants may also receive a CYP450 drug cocktail. The main goal is to check the safety and how the body processes LY3873862 over about 13 weeks.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
LY3873862 or placebo administered orally with a CYP450 drug cocktail
LY3873862 or placebo administered orally with a CYP450 drug cocktail
LY3873862 or placebo administered orally
Find a Clinic Near You
Who Is Running the Clinical Trial?
Eli Lilly and Company
Lead Sponsor
Dr. Daniel Skovronsky
Eli Lilly and Company
Chief Medical Officer since 2018
MD from Harvard Medical School
David A. Ricks
Eli Lilly and Company
Chief Executive Officer since 2017
BSc from Purdue University, MBA from Indiana University
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