Zotatifin + Carboplatin for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
To find the optimal (best) recommended dose of zotatifin and carboplatin to treat patients with metastatic or recurrent TNBC.
Who Is on the Research Team?
Bora Lim, MD
Principal Investigator
UT MD Anderson Cancer Center
Are You a Good Fit for This Trial?
This trial is for adults with advanced or recurrent triple negative breast cancer (TNBC) who have already tried at least two treatments, or those with inflammatory breast cancer. Participants must have good organ function and not be pregnant. People with certain heart, lung, immune conditions, allergies to study drugs, or active infections cannot join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive zotatifin and carboplatin to determine the optimal biologic dose
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Carboplatin
- Zotatifin
Trial Overview
The study is testing different doses of zotatifin combined with carboplatin in people whose TNBC has come back or spread after other treatments. The goal is to find the safest and most effective dose combination.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
Cancer Prevention Research Institute of Texas
Collaborator
SJP Biotec
Collaborator
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