100 Participants Needed

Lung Screening for Lung Cancer

Recruiting at 10 trial locations
AG
FV
Overseen ByFrancis Valenzona
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Hackensack Meridian Health
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

The trial aims to increase lung cancer screening using a tailored educational tool called LungTalk. LungTalk is an interactive program delivered via iPad that adjusts its content based on smoking status and perceived barriers to screening. Researchers will compare participants using LungTalk to another group receiving a standard lung screening pamphlet to determine which method more effectively boosts screening rates. The trial seeks individuals who are current or former smokers, aged 50 to 80, with a significant smoking history and who have never been screened for lung cancer. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could improve lung cancer screening methods.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that the LungTalk Digital Tool is safe for use in lung cancer screening?

Research has shown that LungTalk, a computer-based learning tool, received positive feedback in past studies. In earlier trials, LungTalk doubled participants' knowledge about lung cancer screening and improved their health beliefs without causing major side effects. Participants who used LungTalk were significantly more likely to choose lung cancer screening than those who did not use it. This suggests that LungTalk is safe and effective in promoting lung cancer screening.12345

Why are researchers excited about this trial?

Researchers are excited about LungTalk because it offers a personalized and interactive approach to learning about lung cancer screening. Unlike standard educational brochures that provide generic information, LungTalk tailors its content to the individual's smoking status and perceived barriers, making the information more relevant and engaging. By using a mix of audio, video, and animations delivered through an iPad, LungTalk adapts to different learning preferences, which has been shown to significantly boost knowledge and influence decisions about screening. This innovative approach could lead to more people choosing to undergo lung cancer screening, ultimately improving early detection rates.

What evidence suggests that the LungTalk tool is effective for increasing lung screening uptake?

Research has shown that LungTalk, an interactive educational tool, may help increase lung cancer screening rates. In this trial, participants in the LungTalk Group will use this tool, which earlier studies found more than doubled participants' understanding and beliefs about lung cancer screening. It also significantly increased the number of people deciding to get screened, with nearly twice as many choosing screening compared to those who used a standard pamphlet. LungTalk provides information tailored to a person's smoking habits and concerns, addressing personal worries and encouraging more people to get screened. These findings suggest that LungTalk could effectively promote lung cancer screening.35678

Who Is on the Research Team?

LC

Lisa Carter-Bawa, PhD

Principal Investigator

Hackensack Meridian Health

Are You a Good Fit for This Trial?

The LEAD Study is for individuals aged 50-80 who have a history of heavy smoking (at least 20 pack-years), are current smokers or quit within the last 15 years, and have never had lung cancer screening. Participants must be able to give informed consent and speak English.

Inclusion Criteria

I currently smoke or quit smoking within the last 15 years.
I can speak and understand English.
I am between 50 and 80 years old.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive a tailored lung screening intervention using the LungTalk tool or a non-tailored pamphlet

1 month
1 visit (in-person) for intervention delivery

Follow-up

Participants are monitored for changes in lung cancer screening uptake and related health beliefs

6 months
Assessments at 1 week, 1 month, and 6 months post-intervention

What Are the Treatments Tested in This Trial?

Interventions

  • LungTalk
Trial Overview This study tests 'LungTalk', a tailored intervention to increase lung screening uptake, against non-tailored lung screening advice in the Emergency Department. It aims to see if personalized communication can improve knowledge and attitudes towards lung cancer screening.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: LungTalk GroupExperimental Treatment1 Intervention
Group II: Non-tailored Lung Screening Pamphlet GroupActive Control1 Intervention

LungTalk is already approved in United States for the following indications:

🇺🇸
Approved in United States as LungTalk for:

Find a Clinic Near You

Who Is Running the Clinical Trial?

Hackensack Meridian Health

Lead Sponsor

Trials
141
Recruited
42,900+

New Jersey Commission on Cancer Research

Collaborator

Trials
1
Recruited
100+

Published Research Related to This Trial

A group education class on lung cancer screening significantly improved participants' knowledge, with an average increase of 0.9 correct responses on a true-false quiz after the class, based on surveys from 680 participants.
Approximately 70% of participants felt they had enough information to make informed decisions about lung cancer screening after attending the class, indicating that this educational approach effectively enhances decision-making capacity.
Effectiveness of a Patient Education Class to Enhance Knowledge about Lung Cancer Screening: a Quality Improvement Evaluation.Sakoda, LC., Meyer, MA., Chawla, N., et al.[2021]
Four new scales were developed to measure health beliefs about lung cancer screening in long-term smokers, focusing on perceived risk, benefits, barriers, and self-efficacy, with input from experts and smokers.
Psychometric testing of these scales with 497 long-term smokers showed high reliability (Cronbach's α ranging from .88 to .92) and validity, indicating they can effectively identify smokers more likely to participate in lung cancer screening and inform future interventions.
Development and Psychometric Evaluation of the Lung Cancer Screening Health Belief Scales.Carter-Harris, L., Slaven, JE., Monohan, P., et al.[2018]
The NHS England leaflet for the Targeted Lung Health Check (TLHC) program was generally well-received by 40 current and former smokers aged 55-73, helping them understand the screening process and fostering positive intentions towards participation.
Participants expressed anxiety about potential screening results but felt reassured by the involvement of healthcare professionals; however, they struggled with understanding certain risks and eligibility criteria, indicating a need for clearer communication to support informed decision-making.
Acceptability of a standalone written leaflet for the National Health Service for England Targeted Lung Health Check Programme: A concurrent, think-aloud study.Jallow, M., Black, G., van Os, S., et al.[2022]

Citations

A Brief Report Case Study Using the Lung Cancer Stigma ...The INSPIRE-Lung Study uses a computer-tailored health communication and decision support tool called LungTalk (#NCT05824273). The overarching communication ...
Computer-Tailored Decision Support Tool for Lung Cancer ...LungTalk is a computer-tailored decision support tool that is theoretically grounded in the Conceptual Model on Lung Cancer Screening ...
LungTalk for Increasing Lung Cancer ScreeningThese findings imply that similar tools, such as LungTalk, may also be effective in increasing lung cancer screening by facilitating better communication and ...
A Brief Report Case Study Using the Lung Cancer Stigma ...Effective Communication About Lung Cancer Screening Without Iatrogenic ... Lung Cancer Stigma Communications Assessment Tool of LungTalk. Effective ...
Combatting Stigmatization to Increase Lung Cancer ...According to findings published in JTO Clinical Research and Reports, applying the Lung Cancer Stigma Communications Assessment Tool to LungTalk ...
Leveraging social media to increase lung cancer screening ...Early health communication tools and decision aids for lung screening have ... communication and decision support intervention related to lung screening (LungTalk) ...
Study Details | NCT05824273 | The INSPIRE-Lung StudyLungTalk is a 10-15 minute long computer-tailored health communication and decision-making tool that is theoretically grounded in the Conceptual Model on Lung ...
Effectiveness of Technology-Based Interventions in ...... technology-based tools aiming to increase lung cancer screening uptake. ... Tool for Lung Cancer Screening: Community-Based Pilot Randomized Controlled Trial.
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