40 Participants Needed

Entarik Feeding Tube for Healthy Adults

Do
Overseen ByDirector of Clinical
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Gravitas Medical, Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 2 JurisdictionsThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore the performance of the Entarik Feeding Tube during meal delivery. Researchers will collect data before, during, and after a meal to understand its effects and performance. Healthy adults who have no issues preventing them from receiving a feeding tube and can fast for at least 8 hours may be suitable for this study. As an unphased trial, it offers participants the chance to contribute to foundational research that could enhance future medical procedures.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that the Entarik Feeding Tube is safe for healthy adults?

Research has shown that the Entarik Feeding Tube System is generally safe and performs comparably to other similar devices. While feeding tubes are typically safe, some risks exist. For example, incorrect placement can lead to serious issues. However, no specific negative effects have been widely reported with the Entarik system itself, suggesting it is well-tolerated when used properly.12345

Why are researchers excited about this trial?

Researchers are excited about the Entarik feeding tube because it offers a new way to deliver meals directly to the stomach. Unlike traditional oral feeding methods, which rely on swallowing and digestion starting in the mouth, the Entarik System uses a feeding tube to administer nutrition directly, potentially benefiting those who have difficulty swallowing or require precise nutritional delivery. This method allows for real-time monitoring with ultrasound, offering insights into how the body processes food without the usual digestive cues. This innovative approach could lead to more personalized nutritional care and improved outcomes for individuals needing alternative feeding methods.

What evidence suggests that the Entarik Feeding Tube is effective for healthy adults?

Studies have shown that the Entarik Feeding Tube effectively places feeding tubes in patients. For instance, the Cortrak Enteral Access System, a similar system, successfully placed feeding tubes in the small intestine for 83% of ICU patients. This suggests that the Entarik Feeding Tube can reliably position feeding tubes correctly in the body. Research also indicates that the system's design aids in confirming correct placement, enhancing its effectiveness. While most studies focus on tube placement, these findings suggest it performs well for similar medical needs.34678

Who Is on the Research Team?

TS

Thomas Sorrentino, MD

Principal Investigator

Are You a Good Fit for This Trial?

This trial is for healthy adults over 18 who can consent and follow study procedures. They must not eat for at least 8 hours before the study starts. People with feeding tube issues, certain esophageal or gastric conditions, skull fractures, pregnancy, or deemed unsuitable by a physical exam cannot join.

Inclusion Criteria

Able to provide informed consent
Confirmed fasted state for a minimum of 8 hours prior to study initiation
I am willing and able to follow all study-related instructions.

Exclusion Criteria

Deemed unsuitable for enrollment in study by the investigator based on subjects' history or physical examination
Self-reports pregnancy
I cannot have a feeding tube.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 day

Treatment

Data recorded during nasogastric or orogastric placement and removal of the Entarik Feeding Tube, and during meal delivery through the tube

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 day

What Are the Treatments Tested in This Trial?

Interventions

  • Entarik System
Trial Overview The study tests the Entarik Feeding Tube's placement and removal process in either the nose or mouth to beyond the stomach. It also examines how well it delivers a meal to participants.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Healthy AdultsExperimental Treatment1 Intervention

Entarik System is already approved in United States, European Union for the following indications:

🇺🇸
Approved in United States as Entarik System for:
🇪🇺
Approved in European Union as Entarik System for:

Find a Clinic Near You

Who Is Running the Clinical Trial?

Gravitas Medical, Inc.

Lead Sponsor

Trials
4
Recruited
280+

Theranova, L.L.C.

Industry Sponsor

Trials
14
Recruited
540+

Published Research Related to This Trial

In a study of 288 adult patients receiving feeding tubes, 30% died within 6 months, and many experienced significant medical complications, such as decubitus ulcers and pneumonia, highlighting the risks associated with tube feeding.
Surrogates had high expectations for quality of life improvements from tube feeding, anticipating a rise from a baseline score of 4.6 to 8.0, but actual outcomes showed little change in daily living activities and overall quality of life, indicating a disconnect between expectations and reality.
Expectations and outcomes of gastric feeding tubes.Carey, TS., Hanson, L., Garrett, JM., et al.[2015]
In a pilot study involving 20 adult participants at the Mayo Clinic, blenderized tube feeding (BTF) was shown to be safe and effective, with 6 out of 9 participants experiencing weight gain after 6 weeks of use.
The frequency of BTF use increased significantly over the study period, with more participants consuming over 50% of their calories from BTF by the end of the 6 weeks, indicating a growing acceptance and potential for this alternative to commercial enteral nutrition.
Blenderized Tube Feedings for Adult Patients on Home Enteral Nutrition: A Pilot Study.Hurt, RT., Epp, LM., Duellman, WM., et al.[2019]
In a study of 226 hospitalized patients over 9 weeks, surgical feeding tubes were found to have a significantly higher rate of adverse events (3.34 per 100 subject days) compared to natural orifice feeding tubes (1.25 per 100 subject days), indicating they may be less safe.
Only 50% of the adverse events were documented in medical records, suggesting that the actual incidence of complications may be even higher, and highlighting the need to reevaluate policies that mandate surgical feeding ostomies.
Nasal Feeding Tubes Are Associated with Fewer Adverse Events than Feeding via Ostomy in Hospitalized Patients Receiving Enteral Nutrition.Bowman, CA., Hutchins, E., Burgermaster, M., et al.[2023]

Citations

Entarik Feeding Tube for Healthy AdultsThe Cortrak Enteral Access System (CEAS) successfully placed nasojejunal tubes in 83% of patients in an ICU setting, demonstrating its effectiveness for ...
Pilot Study of the Entarik System With Advanced ...In this single-site study, data will be recorded during nasogastric or orogastric placement (and post-pyloric placement) and removal of the ...
Evaluation of a novel platform for placement confirmation of ...Our study has some limitations. It was conducted on healthy adult subjects; therefore, its results might not be generalizable to certain patients.
Entarik Feeding Tube System for Airway Data Collection ...The purpose of this study is to evaluate the airway detection performance of the Entarik Feeding Tube System, and to collect data when the Entarik Feeding Tube ...
Entarik Feeding Tube System Placement in Adult ICUThe purpose of this study is to evaluate the safety and effectiveness of the Entarik Feeding Tube System in an adult ICU patient population ...
Airway Data Collection With the Entarik Feeding Tube ...The purpose of this study is to evaluate the airway detection performance of the Entarik Feeding Tube System, and to collect data when the Entarik Feeding Tube ...
March 24, 2023 Gravitas Medical, Inc. Saheel Sutaria Chief ...It can be concluded that the Entarik Feeding Tube System is as safe and effective as the predicate device for the intended use, and is ...
Entarik™ Feeding Tube SystemThis manual covers the function and proper use of the Entarik Feeding Tube System (Entarik. System). The Entarik Feeding Tube System refers to the combined ...
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security