Alcohol for Women With History of Sexual Assault

The goal of this clinical trial is to determine whether women who engage in heavy drinking with a history of sexual assault (SA) victimization show heightened baseline reactivity to uncertain threat (U-threat), whether alcohol reduces this reactivity and related anxiety, and how these processes link to real-world drinking behavior. The main questions it aims to answer are:

* Test whether heavy drinking women with a history of SA display exaggerated baseline reactivity to U-threat.

* In the lab, test whether alcohol intoxication is associated with decreases in reactivity to U-threat and subjective anxiety, particularly in heavy drinking women with a history of SA.

* In the real-world, test associations between SA victimization, reactivity to U-threat, alcohol consumption, and anxiolytic relief.

Participants will:

* Complete a screening and orientation session

* Complete two experimental lab sessions that will include intravenous (IV) administration of either 80mg% alcohol or placebo (saline), order counterbalanced

* Complete daily ecological momentary assessments (EMA) surveys for 21 days

* Wear a transdermal alcohol wrist biosensor (BACTrack Skyn) for 21-days