Blueberries for Weight Loss

MK
SH
Overseen ByShirin Hooshmand, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: San Diego State University

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether eating wild blueberries can better control appetite and aid in weight loss compared to a similar calorie intake from a blueberry-flavored syrup. Researchers aim to determine if blueberries can reduce hunger and improve sugar metabolism, potentially leading to more effective weight loss and better health indicators like blood pressure and cholesterol levels. Participants will engage in two phases: first testing immediate effects, then following a longer diet plan with daily blueberry intake. The trial seeks overweight or obese individuals who don't smoke, haven't experienced significant recent weight changes, and aren't allergic to blueberries or yogurt. As an unphased trial, this study offers a unique opportunity to contribute to understanding the health benefits of natural foods.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but it excludes those on medications that may affect body weight or metabolism. It's best to discuss your specific medications with the trial organizers.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that wild blueberries are generally safe and easy to eat. Studies have found that daily consumption of blueberries can help reduce body fat and improve food processing in the body. These studies did not report any major harmful effects from eating blueberries.

Blueberries contain antioxidants and other natural compounds that can lower oxidative stress, reducing damage caused by unstable molecules called free radicals. Their regular use in diets and approval for everyday foods support the safety of wild blueberries.

Overall, eating wild blueberries is considered safe and may offer health benefits, with no major negative effects reported in studies.12345

Why are researchers excited about this trial?

Researchers are excited about the potential of using wild blueberries for weight loss because they offer a natural and tasty approach to managing appetite and weight. Unlike typical weight loss methods that might rely on supplements or medication, these treatments incorporate whole food with antioxidant-rich blueberries, which could help regulate appetite and improve metabolic health. Furthermore, the study explores the use of daily text messaging and at-home weighing, which may enhance adherence and provide real-time feedback, making the process more engaging and personalized for participants. This innovative approach could pave the way for a more enjoyable and sustainable weight loss strategy.

What evidence suggests that this trial's treatments could be effective for weight loss?

This trial will compare the effects of consuming wild blueberries with a placebo on weight loss and appetite regulation. Research has shown that eating blueberries daily can aid in weight loss and reduce body fat. Blueberries contain natural compounds called phenolics and antioxidants, which may help control appetite and improve food metabolism. In studies, participants who ate blueberries experienced fewer food cravings and retained more muscle. Blueberries also seem to influence hunger-related hormones, reducing feelings of hunger. In animal studies, particularly with those prone to weight gain, blueberries helped reduce signs of metabolic issues and excess body fat. Overall, blueberries appear promising for supporting weight loss.12678

Who Is on the Research Team?

SH

Shirin Hooshmand, PhD, RD

Principal Investigator

San Diego State University

Are You a Good Fit for This Trial?

This trial is for overweight or obese men and women with a Body Mass Index (BMI) between 25-40. It's designed to see if wild blueberries help control appetite and support weight loss when mixed into yogurt, compared to a placebo syrup.

Inclusion Criteria

Your Body Mass Index is between 25 and 40, indicating you are overweight or obese.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Phase I - Acute Testing

Participants complete two acute feeding trials to assess the effects of wild blueberries on appetite and glucose metabolism.

1 week
Multiple visits for blood sampling and appetite assessment

Phase II - 8-week Feeding Trial

Participants consume daily servings of yogurt with either wild blueberries or placebo syrup, along with intensive counseling for weight loss.

8 weeks
Bi-weekly visits for counseling and assessments

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Impacts of Wild Blueberries on Appetite and Weight Regulation
Trial Overview The study tests the effects of wild blueberries on appetite regulation and weight loss over two phases: an initial phase assessing immediate impacts on hunger, glucose metabolism, and hormones; followed by an 8-week period where participants eat the yogurt daily while receiving weight loss counseling.
How Is the Trial Designed?
4Treatment groups
Experimental Treatment
Placebo Group
Group I: Blueberries-Phase IIExperimental Treatment1 Intervention
Group II: Blueberries-Phase IExperimental Treatment1 Intervention
Group III: Syrup-Phase IPlacebo Group1 Intervention
Group IV: Syrup-Phase IIPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

San Diego State University

Lead Sponsor

Trials
182
Recruited
119,000+

Citations

Impacts of Wild Blueberries on Appetite and Weight ...The objective is to complete a two-phase study to assess how wild blueberries impact regulation of appetite of overweight and obese men and women as well as ...
Investigation of the impact of blueberries on metabolic ...Blueberries consumed on a daily basis have been shown to significantly reduce weight loss and body fat levels in humans. •. Blueberry phenolics and antioxidants ...
Impacts of Wild Blueberries on Appetite RegulationWe hy- pothesized that wild blueberries would promote positive appe- titive responses by regulating appetite-linked hormones and improving postprandial ...
Recent Research on the Health Benefits of Blueberries and ...Blueberry intake reduced markers of metabolic syndrome and adiposity in high-fat–fed, obesity-prone rats (80).
Blueberries can be a healthy option for patients trying to ...Participants who consumed blueberries had decreased food cravings and tended to preserve their lean body mass. Researchers are planning a ...
Blueberry Consumption and Changes in Obesity ...The effects of blueberries (BB) and bilberries in outcomes related to obesity, metabolic syndrome (MetS), and type 2 diabetes mellitus (T2DM).
Blueberries for Weight Loss · Info for ParticipantsThe hypothesis is that wild blueberries will reduce hunger by regulating appetite hormones and promoting beneficial glycemic and insulinemic responses and that ...
Effects of Wild Blueberries on Fat Oxidation Rates in ...Wild blueberries (WBs) have been documented to decrease oxidative stress in active and sedentary populations as well as influence lipolytic enzymes.
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