Advanced MRI for Brain Tumors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests advanced MRI techniques to help doctors better understand where a brain tumor might recur. Researchers hope these new imaging methods can identify high-risk areas in malignant gliomas (a type of brain tumor) and ensure the treatment remains safe with minimal side effects. Individuals diagnosed with or suspected of having a brain tumor, and who might undergo radiation therapy, may be suitable candidates for this trial. As an unphased trial, participants can contribute to pioneering research that may enhance future brain tumor treatments.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that this advanced MRI is safe for people with brain tumors?
Research has shown that advanced MRI scans are generally safe for people with brain tumors. Many studies have used these scans to help doctors better understand and classify brain tumors. Unlike some other imaging methods, they do not use radiation, making them safer.
Studies also indicate that advanced MRI can be performed without gadolinium-based contrast agents, which can sometimes cause side effects. Avoiding these agents enhances the procedure's safety.
Overall, advanced MRI is well-tolerated, and research has not reported any major side effects from these scans. This makes advanced MRI a safe option for people with brain tumors.12345Why are researchers excited about this trial?
Researchers are excited about the advanced MRI sequences for brain tumors because these sequences offer more detailed images than standard MRI scans. Unlike conventional imaging techniques, advanced MRI can provide early insights into tumor characteristics, potentially improving surgical and radiation planning. This method allows doctors to see beyond the basic structure of the tumor, giving a clearer picture of how aggressive the tumor might be and helping tailor treatment plans more precisely to each patient.
What evidence suggests that advanced MRI is effective for brain tumors?
Research has shown that advanced MRI scans, which participants in this trial will undergo, can aid in diagnosing and understanding brain tumors, such as malignant gliomas. Studies have found that these imaging techniques, combined with machine learning, can predict patient outcomes and identify critical tumor areas. One study discovered that advanced MRI accurately detects changes in tumors, with a sensitivity rate of about 87%. This accuracy makes it particularly effective at identifying dangerous tumor parts that might recur. Advanced MRI also assists in planning treatment and monitoring disease progression. Overall, these imaging techniques hold promise for enhancing how doctors manage brain tumors.16789
Who Is on the Research Team?
Robert Young, MD
Principal Investigator
Memorial Sloan Kettering Cancer Center
Are You a Good Fit for This Trial?
This trial is for adults over 18 with suspected or confirmed high or low grade gliomas, which are types of brain tumors. They should be candidates for radiation therapy and able to consent to the study. It's not suitable for those allergic to MRI contrast agents, have contraindications to MRI like pacemakers, are pregnant/nursing, can't undergo an MRI due to extreme claustrophobia, or cannot cooperate during the procedure.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Preoperative Planning MRI
Advanced MRI studies are obtained at the time of the routinely scheduled preoperative planning MRI
Pre-RT Planning MRI
Advanced MRI studies are obtained at the time of the routinely scheduled pre-RT planning MRI approximately 3±2 weeks after surgery
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- MRI and advanced MRI sequences
Find a Clinic Near You
Who Is Running the Clinical Trial?
Memorial Sloan Kettering Cancer Center
Lead Sponsor