Thomas Marron - Internal Medicine ...

Dr. Thomas Marron, MD PhD

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Icahn School of Medicine at Mount Sinai

Studies Non-Small Cell Lung Cancer
Studies Solid Tumors
14 reported clinical trials
24 drugs studied

Area of expertise

1

Non-Small Cell Lung Cancer

Thomas Marron, MD PhD has run 6 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
RECIST 1.1
2

Solid Tumors

Thomas Marron, MD PhD has run 5 trials for Solid Tumors. Some of their research focus areas include:

Stage IV
Stage III
FGFR2 positive

Affiliated Hospitals

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Icahn School Of Medicine At Mount Sinai

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Ichan School Of Medicine At Mount Sinai

Clinical Trials Thomas Marron, MD PhD is currently running

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RBS2418

for Cancer

This trial is testing a new drug called RBS2418, alone or with pembrolizumab, for patients with advanced tumors who haven't responded to other treatments. The drug works by boosting the body's natural defenses to better recognize and destroy cancer cells.

Recruiting

1 award

Phase 1

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Dupilumab + Cemiplimab

for Early-Stage Lung Cancer

This is a phase 1/2 study of combined treatment with dupilumab (anti-IL-4Ra) and cemiplimab (anti-PD-1) in patients with early-stage, resectable non-small cell lung cancer (NSCLC). The study will include participants with a confirmed diagnosis of NSCLC who are deemed to be surgical candidates, or patients who have a smoking history and radiographic findings highly suggestive if a diagnosis of NSCLC who are scheduled to undergo diagnostic biopsy. On Day 1, participants will receive neoadjuvant therapy consisting of 600 mg of dupilumab (2 SC injections of 300 mg) and 350 mg of IV cemiplimab. Participants will undergo standard of care surgery, which will be scheduled within 7 days of Day 15. Participants will be followed up 30 days following administration of dupilumab and cemiplimab for adverse event (AE) and dose limiting toxicity (DLT) monitoring. Participants will be offered adjuvant therapy as per standard of care, outside the context of this clinical treatment, and undergo subsequent standard of care monitoring for recurrence. The study team will monitor the status of the participant through chart review, or by telephone should the patient not continue to follow with a physician at Mount Sinai, for up to 5 years.

Recruiting

1 award

Phase 1 & 2

10 criteria

More about Thomas Marron, MD PhD

Clinical Trial Related

4 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Thomas Marron, MD PhD has experience with

  • Pembrolizumab
  • Dupilumab
  • Cemiplimab
  • Nivolumab
  • BMS-986253
  • Botensilimab

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