Jane L. Meisel, MD | Winship Cancer ...

Dr. Jane L Meisel

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Winship Cancer Institute / Emory University School of Medicine

Expert in Breast Cancer
Studies Breast cancer
11 reported clinical trials
24 drugs studied

Area of expertise

1

Breast Cancer

Global Leader

Jane L Meisel has run 11 trials for Breast Cancer. Some of their research focus areas include:

Stage IV
Stage III
HER2 negative
2

Breast Cancer

Jane L Meisel has run 5 trials for Breast cancer. Some of their research focus areas include:

Stage I
Stage II
HER2 negative

Affiliated Hospitals

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Winship Cancer Institute / Emory University School Of Medicine

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Emory University Hospital Midtown

Clinical Trials Jane L Meisel is currently running

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Lasofoxifene and Abemaciclib vs Fulvestrant and Abemaciclib

for Breast Cancer

The goal of this clinical trial is to assess the efficacy, safety and tolerability of the combination of lasofoxifene and abemaciclib compared to fulvestrant and abemaciclib for the treatment of pre- and postmenopausal women and men who have previously received ribociclib or palbociclib-based treatment and have locally advanced or metastatic estrogen receptor positive (ER+)/human epidermal growth factor 2 negative (HER2-) breast cancer with an estrogen receptor 1 (ESR1) mutation. The main question the study aims to answer is: • To compare the efficacy of the combination of lasofoxifene and abemaciclib with that of fulvestrant and abemaciclib Participants will receive either receive 5 mg/d of oral lasofoxifene plus oral abemaciclib 150 mg twice a day or the combination of fulvestrant 500 mg intramuscular (IM) on Days 1, 15, and 29 and then once monthly thereafter plus oral abemaciclib 150 mg twice a day.

Recruiting

2 awards

Phase 3

12 criteria

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Pembrolizumab

for Triple-Negative Breast Cancer

This phase III trial compares the effect of continuation of treatment with pembrolizumab (usual approach) to observation only at preventing cancer from coming back in patients with early-stage triple-negative breast cancer (TNBC) who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. The usual approach for patients with early-stage TNBC who receive preoperative chemotherapy plus pembrolizumab is to continue to receive pembrolizumab for up to 27 weeks after surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial may help researchers determine if observation is as good as receiving pembrolizumab for 27 weeks after surgery in triple-negative breast cancer patients who achieved a pathologic complete response after preoperative treatment with chemotherapy and pembrolizumab.

Recruiting

2 awards

Phase 3

19 criteria

More about Jane L Meisel

Clinical Trial Related

3 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Jane L Meisel has experience with

  • Pembrolizumab
  • Tucatinib
  • Trastuzumab
  • Pertuzumab
  • Fulvestrant
  • Web Based App Intervention

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