Dr. Girish Dhall, MD - Neuro-Oncology ...

Dr. Girish Dhall, MD

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Children's Hospital of Alabama

Studies Brain Cancer
Studies Brain Tumor
19 reported clinical trials
38 drugs studied

About Girish Dhall, MD

Education:

  • Obtained MD from the University of Alabama at Birmingham School of Medicine in 2006.
  • Completed Residency in Pediatrics at the University of Alabama at Birmingham in 2009.
  • Finished Fellowship in Pediatric Hematology/Oncology at the University of Alabama at Birmingham in 2012.

Experience:

  • Associate Professor of Pediatrics and Director of the Neuro-Oncology Program at the Children's Hospital of Alabama.

Area of expertise

1

Brain Cancer

Girish Dhall, MD has run 8 trials for Brain Cancer. Some of their research focus areas include:

Stage I
Stage II
Stage IV
2

Brain Tumor

Girish Dhall, MD has run 6 trials for Brain Tumor. Some of their research focus areas include:

Stage IV
Stage III
NF1 positive

Affiliated Hospitals

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Children's Hospital Of Alabama

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University Of Alabama At Birmingham

Clinical Trials Girish Dhall, MD is currently running

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CBL0137

for Cancer

This trial tests CBL0137, a drug that blocks signals inside cancer cells, in patients whose solid tumors, including CNS tumors or lymphoma, have returned or not responded to treatment. By interfering with the cells' internal communication, the drug aims to stop their growth and cause them to die. CBL0137, also known as Curaxin, has shown antitumor activity in multiple cancers, including glioblastoma, renal cell carcinoma, melanoma, neuroblastoma, and small cell lung cancer.

Recruiting

1 award

Phase 1 & 2

13 criteria

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Sodium Thiosulfate

for Hearing Loss in Medulloblastoma

This phase III trial tests two hypotheses in patients with low-risk and average-risk medulloblastoma. Medulloblastoma is a type of cancer that occurs in the back of the brain. The term, risk, refers to the chance of the cancer coming back after treatment. Subjects with low-risk medulloblastoma typically have a lower chance of the cancer coming back than subjects with average-risk medulloblastoma. Although treatment for newly diagnosed average-risk and low-risk medulloblastoma is generally effective at treating the cancer, there are still concerns about the side effects of such treatment. Side effects or unintended health conditions that arise due to treatment include learning difficulties, hearing loss or other issues in performing daily activities. Standard therapy for newly diagnosed average-risk or low-risk medulloblastoma includes surgery, radiation therapy, and chemotherapy (including cisplatin). Cisplatin may cause hearing loss as a side effect. In the average-risk medulloblastoma patients, this trial tests whether the addition of sodium thiosulfate (STS) to standard of care chemotherapy and radiation therapy reduces hearing loss. Previous studies with STS have shown that it may help reduce or prevent hearing loss caused by cisplatin. In the low-risk medulloblastoma patients, the study tests whether a less intense therapy (reduced radiation) can provide the same benefits as the more intense therapy. The less intense therapy may cause fewer side effects. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of cancer cells. The overall goals of this study are to see if giving STS along with standard treatment (radiation therapy and chemotherapy) will reduce hearing loss in medulloblastoma patients and to compare the overall outcome of patients with medulloblastoma treated with STS to patients treated without STS on a previous study in order to make sure that survival and recurrence of tumor is not worsened.

Recruiting

3 awards

Phase 3

More about Girish Dhall, MD

Clinical Trial Related

4 years of experience running clinical trials · Led 19 trials as a Principal Investigator · 9 Active Clinical Trials

Treatments Girish Dhall, MD has experience with

  • Radiation Therapy
  • Vincristine
  • Nivolumab
  • Cyclophosphamide
  • Lomustine
  • Fludarabine

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