Eytan M. Stein, MD - MSK Leukemia ...

Dr. Eytan Stein, MD

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Memorial Sloan Kettering Cancer Center

Studies Acute Myeloid Leukemia
Studies Myelodysplastic Syndrome
14 reported clinical trials
15 drugs studied

Area of expertise

1

Acute Myeloid Leukemia

Eytan Stein, MD has run 9 trials for Acute Myeloid Leukemia. Some of their research focus areas include:

FLT3 positive
IDH positive
U2AF2 positive
2

Myelodysplastic Syndrome

Eytan Stein, MD has run 4 trials for Myelodysplastic Syndrome. Some of their research focus areas include:

U2AF2 positive
U2AF1 positive
ZRSR2 positive

Affiliated Hospitals

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Memorial Sloan Kettering Cancer Center

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Memorial Sloan Kettering Westchester

Clinical Trials Eytan Stein, MD is currently running

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GLB-001

for Acute Myeloid Leukemia

This trial tests a new drug, GLB-001, in patients with certain types of blood cancer that haven't responded to other treatments. The goal is to find out how safe the drug is and what dose works best.

Recruiting

1 award

Phase 1

6 criteria

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BTX-A51

for Leukemia

This is an open-label, dose escalation study to evaluate the safety, toxicity, and pharmacokinetics (PK) as well as preliminary efficacy of BTX-A51 capsules in participants with relapsed or refractory acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). The study will be done in three parts. Part 1a (Monotherapy Dose Escalation) of this study is designed to determine the dose-limiting toxicities (DLTs) and maximum tolerated dose (MTD) of orally administered BTX-A51 in up to 35 participants who are evaluable for toxicity. Once the MTD is determined, it is planned that an additional 15 participants will be enrolled in Part 1b (Monotherapy Cohort Expansion) of this study for additional experience with safety and efficacy, and to determine the recommended Phase 2 dose (RP2D) which may or may not be different from the MTD. After determination of MTD and RP2D from Part 1a, Part 1c (Azacitidine Combination Dose Escalation) will enroll up to 30 participants. Continued treatment will be available under this study protocol for up to eight 28-day cycles (Continued Treatment Phase) if the Investigator judges the benefit outweighs the risk. Once BTX-A51 treatment has completed, participants will be contacted by telephone every 3 months for up to 2 years after their last treatment for survival status and anticancer therapy (Overall Survival Follow-up).

Recruiting

1 award

Phase 1

7 criteria

More about Eytan Stein, MD

Clinical Trial Related

3 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Eytan Stein, MD has experience with

  • Enasidenib
  • Gilteritinib
  • Ivosidenib
  • Venetoclax
  • Azacitidine
  • E7820

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