Muller, Carolyn Y

Dr. Carolyn Y. Muller

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University of New Mexico Cancer Center

Studies Ovarian Cancer
Studies Endometrial Cancer
23 reported clinical trials
44 drugs studied

Area of expertise

1

Ovarian Cancer

Carolyn Y. Muller has run 8 trials for Ovarian Cancer. Some of their research focus areas include:

KRAS positive
NRAS positive
BRCA1 positive
2

Endometrial Cancer

Carolyn Y. Muller has run 7 trials for Endometrial Cancer. Some of their research focus areas include:

HER2 positive
Stage IV
Stage III

Affiliated Hospitals

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University Of New Mexico Cancer Center

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University Of New Mexico

Clinical Trials Carolyn Y. Muller is currently running

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Behavioral Weight Loss + Progestin

for Endometrial Hyperplasia

Up to 60% of endometrial cancer cases are attributed to obesity, in part because obesity promotes development of atypical endometrial hyperplasia (AEH), and up to 40% of women with AEH go on to develop endometrial cancer. The increasing prevalence of obesity in premenopausal women has resulted in increasing rates of AEH in this age group. Hysterectomy with removal of the fallopian tubes and ovaries is 100% effective in preventing endometrial cancer, but this approach results in infertility. Fertility-sparing treatments exist, such as treatment with oral or intrauterine progestin, but these treatments do not work uniformly and do not combat the underlying cause of endometrial cancer, which is obesity and metabolic syndrome. Additionally, up to 41% of women on progestin eventually experience relapse of AEH or endometrial cancer. Third, many patients have insulin resistance that may worsen with progestin therapy. Thus, to improve treatment of AEH and grade 1 endometrial cancer, prevent and reverse endometrial cancer, and allow women to preserve their fertility, the investigators must integrate an effective weight loss strategy to be given with progestin treatment. It is the hypothesis that premenopausal women with AEH desire uterine preservation will be more likely to have atypia-free uterine preservation at one year if they receive progestin in combination with a behavioral weight loss intervention versus progestin plus enhanced usual care.

Recruiting

1 award

Phase 2

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Robotic vs Open Hysterectomy

for Cervical Cancer

This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.

Recruiting

1 award

N/A

8 criteria

More about Carolyn Y. Muller

Clinical Trial Related

1 year of experience running clinical trials · Led 23 trials as a Principal Investigator · 7 Active Clinical Trials

Treatments Carolyn Y. Muller has experience with

  • Paclitaxel
  • Pembrolizumab
  • External Beam Radiation Therapy
  • Cisplatin
  • Quality-of-Life Assessment
  • Questionnaire Administration

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