Dr. Anand Mahadevan
Claim this profileGeisinger Medical Center
Affiliated Hospitals
Geisinger Medical Center
Geisinger Wyoming Valley/Henry Cancer Center
Clinical Trials Anand Mahadevan is currently running
Stereotactic Radiosurgery vs. HA-WBRT + Memantine
for Brain Cancer
Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiation therapy with hippocampal avoidance (HA-WBRT) is when radiation therapy is given to the whole brain, while trying to decrease the amount of radiation that is delivered to the area of the hippocampus. The hippocampus is a brain structure that is important for memory. Memantine is a drug that is given to help relieve symptoms that can be caused by WBRT, including problems with memory and other mental symptoms. Health Canada, the regulatory body that oversees the use of drugs in Canada, has not approved the sale or use of memantine in combination with WBRT to treat this kind of cancer, although they have allowed its use in this study.
Recruiting
2 awards
Phase 3
Stereotactic Radiation + Immunotherapy
for Kidney Cancer
This phase II trial tests whether the addition of radiation to the primary tumor, typically given with stereotactic ablative radiation therapy (SABR), in combination with standard of care immunotherapy improves outcomes in patients with renal cell cancer that is not recommended for surgery and has spread from where it first started (primary site) to other places in the body (metastatic). Radiation therapy uses high energy photons to kill tumor cells and shrink tumors. Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses of radiation over a shorter period and cause less damage to normal tissue. Immunotherapy with monoclonal antibodies, such as nivolumab, ipilimumab, avelumab, and pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Axitinib, cabozantinib, and lenvatinib are in a class of medications called antiangiogenic agents. They work by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving SABR in combination with standard of care immunotherapy may help shrink or stabilize the cancer in patients with renal cell cancer.
Recruiting
1 award
Phase 2
21 criteria
More about Anand Mahadevan
Clinical Trial Related
7 years of experience running clinical trials · Led 12 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Anand Mahadevan has experience with
- Memantine
- Stereotactic Radiosurgery
- Whole-Brain Radiotherapy
- Optune®
- Temozolomide (benzolamide)
- Surgery Post Radiation And Temozolomide (benzolamide)
Breakdown of trials Anand Mahadevan has run
Brain Tumor
Brain Cancer
Glioblastoma
Lung Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Anand Mahadevan specialize in?
Anand Mahadevan focuses on Brain Tumor and Brain Cancer. In particular, much of their work with Brain Tumor has involved Stage IV patients, or patients who are undergoing treatment.
Is Anand Mahadevan currently recruiting for clinical trials?
Yes, Anand Mahadevan is currently recruiting for 2 clinical trials in Danville Pennsylvania. If you're interested in participating, you should apply.
Are there any treatments that Anand Mahadevan has studied deeply?
Yes, Anand Mahadevan has studied treatments such as Memantine, Stereotactic Radiosurgery, Whole-Brain Radiotherapy.
What is the best way to schedule an appointment with Anand Mahadevan?
Apply for one of the trials that Anand Mahadevan is conducting.
What is the office address of Anand Mahadevan?
The office of Anand Mahadevan is located at: Geisinger Medical Center, Danville, Pennsylvania 17822 United States. This is the address for their practice at the Geisinger Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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