Dr. Albiruni Razak | Bras DDP

Dr. Albiruni Razak, MD

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Princess Margaret Cancer Centre

Studies Soft Tissue Sarcoma
Studies Solid Tumors
6 reported clinical trials
10 drugs studied

Area of expertise

1

Soft Tissue Sarcoma

Albiruni Razak, MD has run 3 trials for Soft Tissue Sarcoma. Some of their research focus areas include:

Stage IV
Stage III
HLA-A positive
2

Solid Tumors

Albiruni Razak, MD has run 2 trials for Solid Tumors. Some of their research focus areas include:

Stage IV
Stage III
FGFR2 positive

Affiliated Hospitals

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Princess Margaret Cancer Centre

Clinical Trials Albiruni Razak, MD is currently running

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Circulating DNA Analysis

for Soft Tissue Sarcoma

This research study will collect blood and tumor tissue samples from patients with soft tissue sarcoma to look at circulating tumor deoxyribonucleic acid (DNA). When tumor cells are damaged or die, DNA from the tumor cells are released into the blood stream as the cells break down. This is called circulating tumor DNA. Circulating tumor DNA is an important biomarker that may be used in cancer detection, prediction of treatment response, and disease monitoring.

Recruiting

1 award

N/A

6 criteria

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YL211

for Cancer

This is a multicenter, open-label, Phase 1 study. The study will enroll subjects with advanced solid tumors. It consists of six parts. Objectives for Dose-Escalation Parts (Part 1 and Part 4) To evaluate the safety and tolerability of YL211 as monotherapy in patients with selected advanced solid tumors (Part 1) and in combination with pembrolizumab in patients with second or third line locally advanced unresectable or metastatic non-squamous non-small cell lung cancer (NSCLC) (Part 4) To determine the maximum tolerated dose (MTD) and select the recommended expansion dose(s) (RED(s)) of YL211 as monotherapy in patients with advanced solid tumors (Part 1) and in combination with pembrolizumab in patients with second line locally advanced unresectable or metastatic non-squamous NSCLC (Part 4) Objectives for Backfill Enrollment Parts (Part 2 and Part 5) To better estimate and characterize the safety and efficacy of YL211 as monotherapy in patients with metastatic colorectal cancer (mCRC) or locally advanced unresectable or metastatic NSCLC (Part 2) and in combination with pembrolizumab in patients with previously untreated locally advanced unresectable or metastatic non-squamous NSCLC (Part 5) To select the RED(s) of YL211 as monotherapy in patients with metastatic colorectal cancer (mCRC) or locally advanced unresectable or metastatic NSCLC (Part 2) and in combination with pembrolizumab in patients with previously untreated locally advanced unresectable or metastatic non-squamous NSCLC (Part 5) Objectives for the Dose-Expansion Parts (Part 3 and Part 6) To further characterize the safety and efficacy of YL211 as monotherapy (Part 3) in patients with locally advanced unresectable or metastatic non-squamous or squamous NSCLC and in combination with pembrolizumab in patients with previously untreated locally advanced unresectable or metastatic non- squamous NSCLC (Part 6) To compare the clinical activity of YL211 in combination with pembrolizumab against pembrolizumab, pemetrexed, and platinum-based chemotherapy (cisplatin or carboplatin) in participants with previously untreated advanced unresectable or metastatic non-squamous NSCLC (Part 6)

Recruiting

1 award

Phase 1

2 criteria

More about Albiruni Razak, MD

Clinical Trial Related

5 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Albiruni Razak, MD has experience with

  • Archival Tumor Tissue Collection And Blood Draws
  • Selinexor
  • Pimicotinib(ABSK021)
  • Placebo
  • YL211
  • Irinotecan Hydrochloride

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