Alan Tan, MD | Faculty | RUSH University

Dr. Alan Tan

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Rush University Medical Center

Studies Kidney Cancer
Studies Bladder Cancer
15 reported clinical trials
26 drugs studied

Area of expertise

1

Kidney Cancer

Alan Tan has run 6 trials for Kidney Cancer. Some of their research focus areas include:

Stage IV
TFEb positive
TFE3 positive
2

Bladder Cancer

Alan Tan has run 5 trials for Bladder Cancer. Some of their research focus areas include:

Stage IV
Stage III

Affiliated Hospitals

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Rush University Medical Center

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Vanderbilt University/Ingram Cancer Center

Clinical Trials Alan Tan is currently running

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Immunotherapy + Targeted Therapy

for Genitourinary Cancers

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.

Recruiting

1 award

Phase 2

21 criteria

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Immunotherapy With or Without Surgery

for Kidney Cancer

This phase III trial compares the effect of adding surgery to a standard of care immunotherapy-based drug combination versus a standard of care immunotherapy-based drug combination alone in treating patients with kidney cancer that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as nivolumab, ipilimumab, pembrolizumab, and avelumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Axitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Surgery to remove the kidney, called a nephrectomy, is also considered standard of care; however, doctors who treat kidney cancer do not agree on its benefits. It is not yet known if the addition of surgery to an immunotherapy-based drug combination works better than an immunotherapy-based drug combination alone in treating patients with kidney cancer.

Recruiting

2 awards

Phase 3

16 criteria

More about Alan Tan

Clinical Trial Related

6 years of experience running clinical trials · Led 15 trials as a Principal Investigator · 3 Active Clinical Trials

Treatments Alan Tan has experience with

  • Nivolumab
  • Ipilimumab
  • Pembrolizumab
  • Avelumab
  • Cabozantinib
  • Axitinib

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